Peyronie’s disease is a men’s sexual medical condition that affects the penis and causes it to become bent or curved during an erection. This condition can be very painful and can make sexual intercourse difficult or even impossible. In this article, we will review the symptoms, causes, and treatments for Peyronie’s disease.

Medical history of Peyronie’s disease

Peyronie’s disease is quite common in men nowadays and has been recognized for centuries, although it was only given its current name in the 20th century. In this article, we will take a brief look at the medical history of Peyronie’s disease. The earliest recorded description of Peyronie’s disease can be traced back to the Italian anatomist Falloppio, who described a case of penile curvature in the mid-16th century. In the following centuries, several other physicians described similar cases, although what causes this condition in a man remained largely unknown. It was not until the 18th century that Peyronie’s disease was named after François Gigot de la Peyronie, the personal physician of King Louis XV of France, who was the first to give a detailed description of the condition.

Despite the early recognition of Peyronie’s disease, it was not until the 20th century that significant advances were made in the understanding and treatment of the condition. In the early 1900s, several theories were proposed to explain what causes PD in a man, including trauma, infection, and inflammation. However, it was not until the 1950s that a more detailed understanding of the condition emerged, with the discovery that Peyronie’s disease is caused by the buildup of fibrous tissue in the penis. Since then, a variety of treatments have been developed for Peyronie’s disease, including surgery, medications, and mechanical devices. Surgery remains the most effective treatment option for severe cases of the condition, although it is associated with a range of risks and complications. Medications such as collagenase have also been shown to be effective in some cases, while mechanical devices such as vacuum pumps and penile extenders may be useful for milder cases of the condition. Modern non-invasive treatments are also gaining a lot of popularity in recent times. While several treatment options are available, more research is needed to fully understand the underlying causes of the condition and to develop more effective treatments.


The symptoms of Peyronie’s disease can vary from person to person, but they typically include a curve or bend in the penis during an erection. This curvature can range from mild to severe, and it may be accompanied by pain or discomfort during sexual activity.

In some cases, Peyronie’s disease may also cause a shortening of the penis or a narrowing of the urethra, which can make urination difficult. Other symptoms may include lumps or bumps in the penis, a loss of sensation or numbness in the penis, or a decrease in erectile function.


Exactly what causes PD in men is not known, but it is believed to be the result of repeated injury to the penis. This injury can occur during sexual activity or as a result of other trauma to the penis, such as a sports injury or an accident.

Other factors that may increase the risk of developing PD for men include age, smoking, diabetes, high blood pressure, and a family history of the condition. Antidepressants and beta blockers are two drugs that may raise the chance of acquiring Peyronie’s disease.


There are several options available as Peyronie’s disease treatments, depending on the severity of the condition and the symptoms that are present. These treatment options for PD in men may include:

Medications: Several medications may be prescribed to help reduce pain, inflammation, and scar tissue formation associated with Peyronie’s disease. These medications may include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or collagenase. Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin can help reduce pain and inflammation. Corticosteroids like prednisone may be used to reduce inflammation and help to soften the scar tissue. Collagenase is an enzyme that breaks down collagen, which is a major component of the scar tissue. Collagenase injections may be used to break down the scar tissue and reduce the curvature of the penis.

Vacuum devices: Vacuum devices may be used to help straighten the penis and improve erectile function. These devices work by creating a vacuum around the penis, which helps to increase blood flow and stimulate an erection. VED for Peyronie’s disease works, but patients may find it uncomfortable to use.

Surgery: In severe cases, Peyronie’s disease surgery may be necessary to correct the curvature of the penis. This may involve removing scar tissue or using a graft to help straighten the penis. Several forms of surgery are available, such as:

Nesbit Procedure: In this procedure, a wedge-shaped piece of tissue is removed from the side of the penis opposite to the curve, which helps to straighten the penis.

Penile Prosthesis: In this procedure, an inflatable device is surgically implanted into the penis. When activated, the device fills with fluid, creating an erection.

Plaque Incision and Grafting: In this procedure, the surgeon removes the scar tissue from the penis and replaces it with a graft of healthy tissue.

Penile injections: Penile injections may be used to help improve erectile function and reduce pain and inflammation. These injections may include verapamil, interferon, or other medications. Verapamil and interferon are two medications that may be injected into the penis to help reduce scar tissue formation and improve erectile function

Shockwave therapy: Peyronie’s disease can be treated without surgery with shockwave therapy. Shockwave therapy may be used to help break up the scar tissue that is causing the curvature of the penis. This therapy uses high-frequency sound waves to stimulate blood flow and promote healing. During shockwave therapy for Peyronie’s disease, high-intensity sound waves are sent from a machine to the penis. The plaque that has built up inside the penis is broken up by these sound waves, enabling the body to naturally absorb it. Shockwave therapy for PD uses sound waves that are comparable to those used in lithotripsy, a procedure to remove kidney stones. They are administered using a hand-held gadget that is placed on the penis. This procedure usually takes twenty minutes to perform and is usually conducted at a doctor’s office.

Shockwave therapy is a successful new treatment for Peyronie’s disease, according to some research. According to a research paper that featured in the International Journal of Impotence Research, shockwave therapy significantly reduced erection-related discomfort in men with PD and also improved penile curvature. Another research published in the journal of Sexual Medicine discovered that shockwave therapy significantly improved erectile function in Peyronie’s disease-affected males.

NanoVi: The immune system is strengthened by NanoVi, which also increases vitality and slows the aging process non-invasively and without the use of hazardous chemicals, helping to repair cell damage and DNA within those cells. The endothelial functions in the penis and prostate region also get benefitted while NanoVi does this. NanoVi is effective the most when it is used in conjunction with shockwave therapy and EMTT therapy.

EMTT therapy: Extracorporeal magnetotransduction therapy, commonly referred to as EMTT therapy, is a form of non-invasive therapy produced mainly to treat musculoskeletal pain and other illnesses. When combined with other technologies like shockwave therapy, Tesla Chair, and NanoVi, it has been suggested to greatly alleviate men’s sexual health concerns, including PD. Electromagnetic transduction therapy or EMTT functions at the extremely small cell level. A powerful magnetic field is directed to the endothelial cells present inside the blood vessels of the penis. These endothelial cells give energy, carry nutrients, and contribute in cell regeneration, which speeds up the body’s healing process and returns sexual function to normal levels. 

Counseling: Counseling may be recommended for individuals who are experiencing emotional distress as a result of Peyronie’s disease. This may include therapy or support groups to help individuals cope with the condition and its effects on their sexual health and relationships.


Peyronie’s disease is a condition that can be very painful and can make sexual intercourse difficult or even impossible. There are several treatment options available for PD, including medications, vacuum devices, surgery, penile injections, shockwave therapy, NanoVi, EMTT therapy and counseling. If you are experiencing symptoms of Peyronie’s disease, it is crucial to speak with a reputable healthcare provider to determine the best treatment options for your particular needs. One such reputable healthcare provider is Shockwave Clinics Ltd. which is a UK-based men’s health clinic which specializes in the treatments of ED, PD and other sexual issues. This clinic has mastered the art of treating men with PD, ED and other sexual issues, using revolutionary non-invasive treatment known as shockwave therapy. The clinic also provides excellent EMTT therapy, NanoVi and Functional Magnetic Stimulation (Tesla Chair).

Occasionally, Peyronie’s disease gets healed by itself without any sort of medical help. However, in many cases, the curvature of the penis may worsen over time, leading to increased pain and discomfort during sexual activity. While there are several treatments available for Peyronie’s disease, there is no one-size-fits-all approach. The best treatment plan will depend on the severity of the condition, the individual’s symptoms and medical history, and their personal preferences.